This medicine could impair your pondering or reactions. Be mindful for those who push or do anything at all that needs you to definitely be notify.
modafinil will increase the amount or result of pantoprazole by influencing hepatic enzyme CYP2C19 metabolism. Insignificant/Importance Mysterious. Net effect on pantoprazole actions not known resulting from opposing consequences of CYP450 enzymes; watch
In vitro measurements point out that sixty% of modafinil is certain to plasma proteins at medical concentrations on the drug. This proportion improvements little or no once the focus of modafinil is various.[146]
Belzutifan is actually a CYP2C19 substrate. Coadministration with CYP2C19 inhibitors might improve incidence or severity of adverse effects. Keep an eye on for anemia and hypoxia and decrease belzutifan dose as proposed.
nevirapine will minimize the extent or effect of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Applying alcohol or tobacco with selected medicines may also lead to interactions to manifest. Talk about with the healthcare Skilled the use of your medication with food stuff, alcohol, or tobacco.
eslicarbazepine acetate will raise the stage or effect of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Keep track of.
In determining to employ a drugs, the risks of taking the medication need to be weighed in opposition to The great it'll do. That is a call both you and your physician will make. For this medicine, the following needs to be regarded as:
The effectiveness click here of steroidal contraceptives may very well be diminished when made use of with PROVIGIL and for just one thirty day period just after discontinuation of therapy. Substitute or concomitant methods of contraception are proposed for individuals getting steroidal contraceptives (e.
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dizziness; sleepiness; tiredness; irritability; falls; nausea and vomiting; body weight attain; vertigo (sense of spinning); challenges strolling Commonly; problems with muscle mass coordination; headache; bruising; abdominal suffering; anxiety FYCOMPA is really a controlled substance (CIII) since it could be abused or cause drug dependence.
cannabidiol will boost the stage or influence of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep track of Intently. Think about minimizing the dose of delicate CYP2C19 substrates, as clinically ideal, when coadministered with cannabidiol.
encouraged for folks just starting out with modafinil. It could potentially cause panic, insomnia, as well as other Unwanted side effects. If you want to do this dose, even if you have a bigger than typical Establish, you must always Make the dose up little by little from possibly 50 mg or a hundred mg.
Some others find 100mg Modafinil in the morning and One more 100mg just after lunch has a tendency to be preferable. This retains a gentle flow of Modafinil to the brain whilst providing an extra publish-lunch Enhance.